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Wife Portia de Rossi - Like her wife, actress Portia de Rossi, DeGeneres was born in January.

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Mama Betty - Her journey begins with her mom, Betty DeGeneres, with whom DeGeneres is very close.

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Stand-up - She began her career as a stand-up comedian.

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Start in television - In the early 1990s, she was a regular on shows like 'Open House' and 'Laurie Hill.'

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'Coneheads' - In 1993, DeGeneres appeared in 'Coneheads.'

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'Roseanne' - In 1995, she appeared in 'Roseanne.'

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'Mr. Wrong' - In 1996, she had her first starring role in a film, 'Mr. Wrong,' alongside Bill Pullman.

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Coming out - DeGeneres came out as a lesbian in 1997.

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Oprah - She made the announcement on 'The Oprah Winfrey Show.'

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First Emmy win - That same year, she won her first Emmy, in the category of Outstanding Writing for a Comedy Series.

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Ramifications - Like DeGeneres, actress Laura Dern saw few acting roles come her way after appearing in the coming out episode of 'Ellen.'

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Anne Heche - DeGeneres began dating actress Anne Heche shortly after coming out publicly.

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'Goodbye Lover' - DeGeneres appeared alongside Patricia Arquette in 'Goodbye Lover' in 1998.

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'Mad About You' - In 1998, she made a small appearance on popular TV show 'Mad About You.'

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'The Larry Sanders Show' - She made two appearances on 'The Larry Sanders Show' from 1996 to 1998.

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'Doctor Dolittle' - She voiced a dog in 'Doctor Dolittle' in 1998.

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From 'Ellen' to 'Edtv' - By the time she appeared in 'Edtv' with Matthew McConaughey in 1999, her sitcom 'Ellen' had been cancelled.

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'The Love Letter' - She starred alongside Tom Selleck in 'The Love Letter' in 1999.

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'If These Walls Could Talk 2' - She played Sharon Stone's lover in the TV movie 'If These Walls Could Talk 2' in 2000, which was directed by her girlfriend Anne Heche.

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Alexandra Hedison - By 2001, DeGeneres was dating Alexandra Hedison.

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Hosting the Emmys - DeGeneres hosted the Emmys in 2001.

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That Björk dress - She famously wore Björk's swan dress during the ceremony.

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'Will & Grace' - DeGeneres appeared on 'Will & Grace' in 2001.

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'Reaching Normal' - Also in 2001, she had a role in 'Reaching Normal' with Andie MacDowell.

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'The Ellen Show' (2001-2002) - Unfortunately, her second attempt at a sitcom only lasted one season.

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Ellen at the center - DeGeneres was the center square on 'Hollywood Squares' from 2002 to 2003.

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'Finding Nemo' changes everything - DeGeneres voiced Dory in 'Finding Nemo' in 2003, a move that changed her career trajectory for the better.

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'The Funny Thing Is...' - She releases 'The Funny Thing Is...' in 2003.

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'The Ellen DeGeneres Show' - And landed her own talk show, 'The Ellen DeGeneres Show.'

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Playing herself - From 2003 to 2005, she played herself in 'Pauly Shore Is Dead,' 'The Bernie Mac Show,' 'Six Feet Under,' and 'Joey.'

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Carrying the Olympic torch - In 2004, DeGeneres had the honor of carrying the Olympic torch.

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Spiderwoman - She also made a hilarious Spiderman at the 2004 MTV Movie Awards.

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Best host - She won Best Talk Show Host at the Emmys in 2004, an award she would go on to earn many more times.

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People's Choice Awards - She's also a legend at the People's Choice Awards. With well over a dozen awards to her name, she has the most earned by anyone.

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Teens think she's cool - DeGeneres has picked up several surfboards at the Teen Choice Awards as well.

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Kids love her - She's also picked up several statues at the Nickelodeon Kids' Choice Awards.

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Romance blooms - In 2004, DeGeneres started dating her future wife, Portia de Rossi.

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Hosting the Oscars - DeGeneres hosted the Oscars for the first time in 2007.

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Covergirl! - She became a Covergirl in 2008.

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Special causes - Famously charitable, DeGeneres performed at the Stand Up To Cancer event in 2008.

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Comedy specials - She taped 'Ellen's Even Bigger Really Big Show' in 2008. She also had comedy specials in 2000 and 2003.

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'American Idol' - Already a fan of the show, DeGeneres became a judge on 'American Idol' in 2010, but left after finding it too critical a role.

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'The Simpsons' - She voiced herself on 'The Simpsons' in 2010.

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Animal lover - A big animal lover, DeGeneres was there for the US Postal Service's dedication of their new Animal Rescue: Adopt A Shelter Pet Stamp in 2010.

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Runway model - That same year she walked the runway with designer Richie Rich during Mercedes-Benz Fashion Week.

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Hollywood Walk of Fame - In 2012, she got a star on the Hollywood Walk of Fame.

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Mark Twain Prize for American Humor - A huge honor for DeGeneres in 2012: the Mark Twain Prize for American Humor.

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Ellen goes to Australia - In 2013, DeGeneres took her talk show overseas to her wife's homeland of Australia.

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The Grammys - DeGeneres presented alongside Beyoncé at the Grammys in 2013.

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More charity - Also in 2013, DeGeneres was there for the launch of the Duracell Power a Smile Program.

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Hosting the Oscars again - She hosted the Oscars again in 2014.

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Famous selfie - She is remembered for the selfie she took during the ceremony, which quickly went viral.

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'Ellen's Design Challenge' - Beginning in 2015, she could also be seen on her reality show, 'Ellen's Design Challenge.'

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'One Big Happy' not so happy - But that same year the sitcom she executive produced, 'One Big Happy,' failed to make it past six episodes.

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'The Big Bang Theory' - In 2016, she played herself on 'The Big Bang Theory.'

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'Finding Dory' - That year her voice was also the star of 'Finding Dory,' the sequel to the film that put her back on the map.

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The Presidential Medal of Freedom - And then came perhaps the highest honor of all: the Presidential Medal of Freedom.

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Disaster relief concert - DeGeneres participated in 'One Voice: Somos Live! A Concert For Disaster Relief' in 2017.

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'Ellen's Game of Games' - Known for playing games on her talk show, DeGeneres got her own game show in 2017.

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